Top 5 Essential Oils for Mast Cell Activation Syndrome

“With one good sniff, my headache was gone. It was so dramatic. I was hooked on Frankincense and wanted to find out more.” 

Headaches can be just one symptom of Mast Cell Activation Syndrome, something many people are dealing with which has been activated by having Covid according to research

What is Mast Cell Activation Syndrome?

Cells that are produced in the soft tissue and bone marrow become activated and release histamine and other mediators that try to fight against something foreign to the body. 

It can be toxins, parts of a virus, allergen, affecting the (lipoprotein polysaccharide)  envelope surrounding the virus. When there's an infection in the body and the body is fighting it, some particles are still floating around, so the body looks at it as a particle that is foreign and attacks it. The way it does this is by releasing inflammatory mediators and the mast cells are activated - histamine, cytokine and more. The latest virus and the ‘treatments’ are parts of the virus lingering because the immune system did not fight it off. 

Triggers such as lack of sleep, nutritionally deficient food, environmental toxins and allergens can cause the immune system to be overactive, and therefore cause a weakened immune system. 

Are you healthy? 

A high percentage of people are not in optimum health, according to the standards of Functional Medicine. 

One can be pre-diabetic even though their sugar tests are normal. Someone can be very thin, but eat a lot of carbs and when you don’t eat healthy foods such as vegetables, the microbiome in the body is unstable. 

How to Support Your Immune System 

  • Eat a whole foods, nutrient-dense diet.
  • Cut out sugar and refined starches.
  • Ensure adequate protein intake.
  • Add garlic, onions, ginger, and lots of spices (oregano, turmeric, rosemary) to your meals.
  • Eat multiple servings of colorful fruits and vegetables
  • Avoid fermented probiotic foods
  • Drink plenty of fluids.
  • Get sufficient sleep. Sleep is crucial, it is when the body rebuilds.
  • Get regular exercise.
  • Practice meditation and yoga.
  • Start a garden.
  • Stay connected. Being in close touch with those you love is essential for your mental and emotional health.
  • Get outside. Talk walks, get fresh air.

Dr. Mark Hyman

Check your blood work for vitamin D, A, K, magnesium and zinc levels and balance them. 

NO QUICK FIX - it takes time - balance everything. You  can't ignore sleep, food or stress. 

Common symptoms include: 

  • poor digestion,
  • food sensitivities,
  • chemical/environmental sensitivities,
  • pruritus,
  • Headaches, brain fog
  • Skin irritation, itchiness
  • urticaria,
  • hypotension,
  • tachycardia,
  • anxiety /depression,
  • chronic fatigue.


MCAS (Mast cell activation syndrome) patients often benefit from strong immune modulators, nervous system trophorestorative, and mucilaginous herbs that soothe and heal the GI system. Immune modulatory herbs serve to “retrain” a hyper-reactive immune response. In MCAS, patients either produce too many mast cells or trigger the ones they have more readily. 

The clinician must determine what each patient’s triggers are and address each of those as well. Inflammation modulators aid in immune cell regulation, helping to retrain the inflammatory cascade. 

Essential oils are a natural substance extracted from plants and

can support your body with: 

  • Support of the Immune system
  • Relieve Stress, anxiety & joint and muscle pain
  • Anti-inflammatory
  • Mast cell stabilization
  • Antimicrobial, antibiotic, antiviral, and antiseptic properties
  • Healthy heart and skin
  • Healthy respiratory system 

Top 5 Essential Oils to reduce Mast Cell Activation and inflammation, and have an immomodulary effect: 

Turmeric Essential Oil (Curcuma Longa) - Inflammation modulator 

Frankincense Essential Oil (Boswellia serrata) - Anti-inflammatory, supports respiratory health, anti-microbial, reduces stress, eases joint/muscle soreness 

Skullcap Essential Oil (Scutellaria baicalensis) - Immune cell regulation, helping to retrain the inflammatory cascade 

Ginger Essential Oil - Promotes mast cell stabilization, contains antioxidants, mood enhancer, supports digestion 

Cinnamon Bark Essential Oil - antihistamine 

How to use: 

Diffusion:  Place a few drops of essential oil in a diffuser. When you inhale the aroma of an essential oil, it enters your bloodstream and then is carried through the body. 

Order the blend with Frankincense, turmeric, ginger & cinnamon bark here.  (need link to product) 

This is a wake up call for our complete health that began 2 years ago. 

People wanted a quick fix so they could be immune to disease easily, but it’s not about a quick fix. People are still getting sick and have a harder time recovering, because the immune system is weakening.  

Our body needs the right conditions to fight this particular virus - all the elements must be in place.

About the author, Liat Chiprut

Liat Chiprut is a Functional Medicine Practitioner and licensed pharmacist. As an essential oil expert, Liat spent years researching and training on the root cause of disease and how to prevent illness and heal the body naturally. Her mission is creating new blends and helping all those that want to heal naturally have the information and products to do so.